INTRODUCTION

Nebidon H Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It helps to control blood pressure when a single medication is not effective. It also helps to reduce chances of any future heart attack and stroke.

Nebidon-H Tablet should be taken with or without food preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

Nausea, constipation, fatigue, headache, and shortness of breath are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away.  Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness or headache may occur due to low blood pressure, hence rise slowly from sitting position or avoid driving.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, blood sugar level and the levels of salts such as potassium or magnesium checked regularly to make sure that this medicine is working properly.

USES OF NEBIDON- H TABLET

• Hypertension (high blood pressure)
• Hypertension (high blood pressure)

• Description of Hypertension (high blood pressure)

• Introduction 

• Hypertension is a condition in which the blood vessels have persistently raised pressure. 

• Blood pressure is one of the vital signs of life. It is the pressure exerted by the blood against the walls of your blood vessels. In hypertension, the blood exerts increased pressure on the walls of the vessels. Therefore, it is also called high blood pressure. It is measured in millimeters of mercury (mmHg) and expressed as systolic/diastolic blood pressure. ‘Systolic’ is the maximum pressure exerted when your heart contracts to pump blood. ‘Diastolic’ is the minimum pressure exerted when your heart is at rest between contractions. 

• Some people may have high blood pressure readings when measured at the doctor’s clinic but normal blood pressure readings when measured at home or while performing their routine activities (ambulatory blood pressure). This condition is termed white coat hypertension. In contrast, some people may have normal blood pressure readings when measured at the doctor’s clinic but consistently above normal blood pressure readings when measured at home or while performing their routine activities. This condition is termed masked hypertension.

• According to A Global Brief on Hypertension published by the World Health Organization, “Hypertension is defined as a systolic blood pressure equal to or above 140 mmHg and/or diastolic blood pressure equal to or above 90 mmHg.”

• According to the American Heart Association (AHA) 2017 guidelines, hypertension is defined as systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg.

• Types:

• There are two main types of hypertension:

• 1. Essential hypertension – It is the type of high blood pressure which has no obvious underlying medical condition. It has three subtypes:
  
  
• Systolic hypertension in teenagers and young adults – It occurs mainly in people aged between 17-25 yrs of age. Its prevalence varies and may reach up to 25% in young men. There is an underlying sympathetic system overactivity.
  
  
• Diastolic hypertension in middle age – It is a condition in which both the systolic and the diastolic blood pressures are elevated. It mostly occurs in patients between 30-50 yrs of age and is associated with weight gain.
  
  
• Isolated systolic hypertension in older adults – It is a condition in which the systolic blood pressure is increased and the diastolic blood pressure is normal or lower. Therefore, the difference between the systolic BP and diastolic BP is increased. It is often seen in older people with hypertension.

• 2. Secondary hypertension – This type of high blood pressure is caused as a result of some underlying medical conditions of the kidneys, heart, blood vessels, or endocrine (hormonal) system. Some of the common causes are renal parenchymal disease, acute/chronic renal diseases, renovascular hypertension, endocrinal causes like pheochromocytoma, acromegaly, hypothyroidism, hyperparathyroidism, etc. and coarctation of aorta, especially in young people with high blood pressure.

BENEFITS OF NEBIDON-H TABLET

In Hypertension (high blood pressure)

Nebidon -H Tablet blocks the effects of some chemicals on your heart and blood vessels. This slows down your heart rate and helps the heart beat with less force. Additionally, it eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

SIDE EFFECTS OF NEBIDON-H TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nebidon-H

• Nausea
• Constipation
• Diarrhea
• Fatigue
• Dizziness
• Headache
• Increased blood uric acid
• Decreased potassium level in blood
• Glucose intolerance
• Altered blood lipid level
• Breathlessness
• Swelling of hands
• Feet swelling
• Paresthesia (tingling or pricking sensation)
• Decreased magnesium level in blood
• Increased calcium level in blood

HOW TO USE NEBIDON-H TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nebidon-H Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW NEBIDON-H TABLET WORKS

Nebidon-H Tablet is a combination of two blood-pressure lowering medicines: Nebivolol and Hydrochlorothiazide. Nebivolol is a beta blocker which works specifically on the heart to reduce heart rate and make the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.